Bovine Leukemia Virus High Tax Molecular Clone Experimentally Induces Leukemia/Lymphoma in Sheep
نویسندگان
چکیده
منابع مشابه
Determination of Lymphocyte Subsets and Pcna Activity in Sheep Experimentally Infected with Bovine Leukemia Virus (blv)
Lymphocyte phenotypes were determined in sheep experimentally infected with bovine leukemia virus (BLV). BLV infection was detected by serological tests AGID and ELISA. Flow cytometry analysis with the use of specific monoclonal antibodies for CD markers and conjugates labeled with FITC or PE was performed. Proliferating cell nuclear antigen (PCNA) was estimated in lymphocytes of infected and h...
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Ruminants often carry gastrointestinal Shiga toxin (Stx)-producing Escherichia coli (STEC). Stxs belong to a large family of ribosome-inactivating proteins (RIPs), found in many plants and some bacteria. Plant RIPs, secreted into extracellular spaces, limit the spread of viruses through plant tissues by penetrating and killing virally infected cells. Previously, we showed Stx activity against b...
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Lymphocyte homeostasis is the result of a critical balance between cell proliferation and death. Disruption of this subtle equilibrium can lead to the onset of leukemia, an increase in the number of lymphocytes being potentially due to both of these parameters. The relative importance of cell proliferation vs. apoptosis during pathogenesis induced by the primate T cell lymphotropic viruses and ...
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BACKGROUND: Bovine leukemia virus (BLV) is an oncogenic deltaretrovirus causing a persistent lifelong infection of B lymphocytes. In addition to the domestic cattle, the virus can also infect water buffaloes. OBJECTIVES: Recent investigations have demonstrated the increasing prevalence of BLV infection among cattle population in Iran. Large popul...
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Sixty-nine sheep were infected with bovine leukemia virus from bovine lymphosarcoma materials. Twenty-four developed lymphosarcoma and died from 13 to 66 (average, 29) months later. Circulating lymphocytes were increased to leukemia levels (70,000 to 403,000/cu mm blood) in only eight sheep within 2 to 3 months of death. Various lymph nodes and visceral organs including heart, abomasum, uterus,...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2005
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.67.1231